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Re: Latest medication news
From: wildbilly@withouta.net (Billy)
Doug Freyburger <dfreybur@yahoo.com> wrote:
Billy wrote:Yeah, maybe, just call me suspicious. People who pay for studies usually
Watcha' doin' Doug? Tryin' to commit suicide by newsgroup?
Chortle. Serotonin is a part of the metabolic puzzle. With no
expectations that a drug about it, the simple fact that it is seeing
studies is a good thing.
get the information that they want. I'm happier that Arena
Pharmaceuticals' (a drug manufacturer) doctors are part of the test,
rather than some poor unfortunate lab rats. They seem to be looking at
it as a magic pill that will let you continue eating crap (the ideal
product), and lose weight at the same time.
<>
"Among those who remained (1/4), lorcaserin produced relatively modest
weight loss when combined with diet and exercise counseling, and that
weight loss was maintained in over half of the participants only so long
as they kept taking the drug. And the paper made **no mention of the
costs** attached to long-term pharmacotherapy," Katz added." (emphasis
mine)
"This close look at lorcaserin reaffirms that better daily use of feet
and forks holds far greater promise for meaningful, sustainable and
affordable weight control than pharmacotherapy," Katz said."
OK, then I'll put the "Tang" back.
I suspect
that the participants ate a low fat diet, since that seems to be
institutional wisdom, and the report was sponsored by Arena
Pharmaceuticals, of San Diego, Calif., which used its own doctors as
part of the study group.
The report didn't list their diet type. I considered the study too
early in any development cycle for that to matter. I saw it as a first
step in a learning process so I was not worried about that.
Serotonin or not, I don't think Susan will be
amused by the pill taking verses diet approach to weight loss.
Lot's of people want a magic pill that burns away the fat. The
pharmaceutical industry absolutely wants such a pill. I get that very
many of the folks reading the article wondered if it might lead to such
a product. I think all or most of the long term regulars on ASDLC have
seen pills making such claims come and go and we'd expect the next in
the line to follow the same pattern. The regulars here have extra
skepticism based on that experience and I knew that. And so that's not
why I found the topic of potential interest. To me if I learn how to
control the hormone by non-medical means that's the interesting part.
Serotonin is a topic she has expressed interest in and it is a hormone
that is a part of the low carb puzzle. That's why I'm interested.
I've seen complaints that low carbing is associated with lowered
serotonin levels, that lowered serotonin causes anxiety and that's why
low carbing is bad. To me that's just another example of why staying at
20 more than two weeks is not optimal. Susan has urged folks to get
their serotonin levels checked.
Once there's awareness that a hormone is involved in carb metabolism
there is study of it, study of meds to effect it, and eventually study
of how to effect it through diet. I don't see this proposed new med as
an end of its own. I see it as a step in that process.
"What's most impressive about this two-year clinical trial is how
unimpressive it is," said Dr. David L. Katz, director of the Prevention
Research Center at Yale University School of Medicine.
That too. But I'm not looking at it in terms of how well it works as a
magic pill to make fat disappear.
--
- Billy
"Fascism should more properly be called corporatism because it is the
merger of state and corporate power." - Benito Mussolini.
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